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Home - Products - GPCR/G Protein - Melanocortin Receptor - RO 27-3225

RO 27-3225

CAS No. ——

RO 27-3225( RO27-3225 | RO 273225 )

Catalog No. M16959 CAS No. ——

RO 27-3225 (RO27-3225, RO 273225) is a potent, selective melanocortin melanocortin receptor MC4R agonist with EC50 of 1 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    RO 27-3225
  • Note
    Research use only, not for human use.
  • Brief Description
    RO 27-3225 (RO27-3225, RO 273225) is a potent, selective melanocortin melanocortin receptor MC4R agonist with EC50 of 1 nM.
  • Description
    RO 27-3225 (RO27-3225, RO 273225) is a potent, selective melanocortin melanocortin receptor MC4R agonist with EC50 of 1 nM, >30-fold selectivity over MC3R; shows some activity at the MC1 receptor (EC50=8 nM), reverses hemorrhagic shock, reduces multiple organ damage, and improves survival.Obesity Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    RO27-3225 | RO 273225
  • Pathway
    GPCR/G Protein
  • Target
    Melanocortin Receptor
  • Recptor
    Melanocortin Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    ——
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CCCC(NC(C(NC(CC1=CC=CC=C1)C(NC(CCCNC(N)=N)C(NC(CC2C(C=CC=C3)=C3NC2)C(N(C)CC(N)=O)=O)=O)=O)=O)CC4=CNC=N4)=O
  • Chemical Name
    Butir-His-D-Phe-Arg-Trp-Sar-NH2 trifluoracetate salt

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Spaccapelo L, et al. Eur J Pharmacol. 2011 Nov 30;670(2-3):479-86. 2. Minutoli L, et al. Crit Care Med. 2011 May;39(5):1089-96. 3. Benoit SC, et al. J Neurosci. 2000 May 1;20(9):3442-8. 4. Agosti F, et al. Eur J Neurosci. 2014 Sep;40(5):2755-65.
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